The occurrence of pain after a major surgery that includes incision and grafting is known as postoperative pain. It may exist for 2-5 days, and proper management is essential to get rid of it. Inadequate control may result in immobility, slower restoration of function, and delayed recovery. The goal is to reduce discomfort with minimum side effects. Despite years of advances in pain treatment, postoperative therapy’s mainstay is still anesthetics like Ketamine powder for sale. They bind to receptors in the central nervous system and block pain signals. It has a rapid onset of action with peak effects within an hour. Those administering the drug should make sure there are no lethal interactions.